Carboxylesterase inhibitors: an update

LW Zou, Q Jin, DD Wang, QK Qian… - Current medicinal …, 2018 - ingentaconnect.com
… group of these compounds was essential for carboxylesterases inhibition, while the introduction
of … for carboxylesterases inhibition. A series of synthesized phosphorylated flavonoids

[PDF][PDF] Synthesis of phosphorylated chrysin derivatives and estimation of efficiency and selectivity of their inhibitory activity towards carboxylesterase

VV Abzianidze, DS Prokofieva… - Russian Journal of …, 2016 - academia.edu
… The data on inhibitory activity of dimethyl and diethyl phosphorylated … as the starting
flavonoid due to high inhibitory activity and selectivity of its diethyl phosphorylated derivative [7]. …

Conifer flavonoid compounds inhibit detoxification enzymes and synergize insecticides

Z Wang, Z Zhao, X Cheng, S Liu, Q Wei… - Pesticide biochemistry …, 2016 - Elsevier
… demonstrated that flavonoid compounds have both in vitro and in vivo esterase inhibition,
which … Several synthesized, phosphorylated flavonoids were identified as potent and selective …

[PDF][PDF] Carboxylesterase inhibitors: an update

LW Zoua, Q Jina, DD Wanga, QK Qiana… - Current Medicinal …, 2018 - researchgate.net
… , while the introduction of phosphate group to target compounds were likely beneficial for
carboxylesterases inhibition. A series of synthesized phosphorylated flavonoids exhibited sig…

Carboxylesterase Inhibitors: Relevance for Pharmaceutical Applications

LW Zou, GB Ge - Pharmaceutical Biocatalysis, 2019 - taylorfrancis.com
… A series of synthesized phosphorylated flavonoids exhibited significantly improved inhibition
potency towards porcine … These phosphorylated flavonoids were irreversible competitive …

Regulations of xenobiotics and endobiotics on carboxylesterases: a comprehensive review

Y Xu, C Zhang, W He, D Liu - European journal of drug metabolism and …, 2016 - Springer
inhibitory activities of 19 synthesized phosphorylated flavonoids and 10 parent flavonoids
against porcine liver … The phosphorylated flavonoids inhibited CES effectively and irreversibly …

[HTML][HTML] Can We Improve Diosmetin Activity? The State-of-the-Art and Promising Research Directions

M Wujec, M Feldo - Molecules, 2023 - mdpi.com
… The phosphorylated flavonoids were tested for the inhibition of carboxylesterases [32]. This
is a family of enzymes … Some of these phosphorylated flavonoids were identified as potent …

Efficient Synthesis of Phosphorus/Nitrogen‐Containing Chrysin Derivatives via Classic Reactions

Z Zeng, S Liu, W Luo, J Liang, AY Peng - ChemistrySelect, 2021 - Wiley Online Library
phosphorylated flavonoids and identified 7-phosphorylated chrysin as the most effective
and selective inhibitor of … esterase (CEase) and porcine liver carboxylesterase (CE) with low …

Carboxylesterase inhibitors from clinically available medicines and their impact on drug metabolism

YQ Song, Q Jin, DD Wang, J Hou, LW Zou… - Chemico-Biological …, 2021 - Elsevier
… in discovery of hCES inhibitors from clinically available … Three comprehensive lists of hCES
inhibitors deriving from … , alongside with their inhibition potentials and inhibition parameters, …

Recent developments of flavonoids with various activities

ZG Sun, ZN Li, JM Zhang, XY Hou… - Current Topics in …, 2022 - ingentaconnect.com
… Compound 3 (IC50 㸺 50 ȣM) displayed the most potent inhibition … potent telomerase inhibitors
derived from flavonoids [23]. … develop more effective flavonoidtype hCE2 inhibitors [152]. …